The revolver. Sometimes referred to as the wheel-gun or the six-shooter, was developed, as we know it today, by Samuel Colt in the 19th Century. It is considered obsolete by modern firearms standards. Although no longer used as a front line weapon in the real world, it seems to have earned a new lease on life in the realms of Science Fiction and Fantasy, especially in the video game industry.
In the Darksiders universe, the Horseman Strife uses a pair of revolvers which are referred to as Mercy and Redemption. Characters in the Destiny game gain access to revolver-like weapons called hand cannons. This could be due to the fact that the revolver, despite being limited on capacity of rounds, are usually more durable and sturdy. It could also be because the six-shooter has an old school coolness factory in regards to appearance. Whatever the reason, I, for one welcome the presence of the wheel-gun in the fictional universes of our time.